孙成鹏，男，博士，教授，博士生导师。近年来，基于靶点“垂钓”技术，围绕中药药效物质和作用靶标，开展中药化学生物学研究，以第一/通讯作者在PNAS、ACS Cent. Sci.、J. Hazard. Mater.、APSB、Chin. Chem. Lett.、J. Med. Chem.、Int. J. Biol.Macromol.等期刊发表SCI论文68篇，其中6篇IF>10，1 篇10>IF>9，29 篇9>IF>5，高被引论文2篇，研究成果连续入选2022和2023年度中医药十大学术进展。主持国家级课题3项，省市课题5项，授权发明专利12项，参编教育部“101计划”中药化学等教材6部。入选天津市和辽宁省青年科技人才项目和中华中医药学会青年人才托举工程，获中华中医药学会青年科技创新奖、天津市科技进步一等奖和辽宁省科技进步二等奖。

获奖：

1. 获中华中医药学会青年科技创新奖(排名第1)

2. 获天津市科技进步一等奖(题目：中药功效关联活性物质发现和机制解析技术体系的创建及应用, 2025, 排名第7)

3. 获辽宁省科技进步二等奖(题目：中药与代谢功能酶的互作平台在中药药效物质挖掘与临床合理使用中的应用，2019，排名第6)

4. 孙成鹏团队研究成果入选2023 年中医药十大学术进展

5. PNAS论文入选2022 年中医药十大学术进展

6.获第十五届“挑战杯”辽宁省大学生课外学术科技作品竞赛中荣获优秀指导教师

7.指导学生获得第十五届挑战杯辽宁省大学生课外学术科技作品竞赛二等奖

8. 2020和2022年指导学生获得挑战杯辽宁省大学生创业计划竞赛铜奖

9. 指导学生获得校级第八届和第九届“互联网+”大学生创新创业大赛获得二等奖和优秀奖

10. 指导学生获得校级第十届“挑战杯”大学生课外学术科技作品竞赛获得二等奖

11. 2021年和2022年指导学生获得校级大学生创新创业训练计划项目获得二等奖和三等奖

学术组织兼职：

1. 中国康复医学会药学与康复专业委员会常务委员

2. 世界中联中药化学专业委员会理事

3. 世界中联中药分析专业委员会理事

4. 中华中医药学会中药实验药理分会委员

5. 中国仪器仪表学会药物质量分析与过程控制分会理事

6. 中华中医药学会中药化学分会青年委员

7. 中国药理学会神经精神药理学专业委员会青年委员

8. 中国药理学会药物代谢专业委员会青年委员

9. Chinese Journal of Natural Medicine，青年编委

10. Acupuncture and Herbal Medicine，青年编委

11. Acta Materia Medica，青年编委

12. Medicinal Plant Biology，青年编委

13. 药学研究，编委

14. BMC Complementary Medicine and Therapies 客座编辑

15. Frontiers in Chemistry 客座编辑

科研及人才项目:

1. 基于靶点垂钓-代谢过程-异常免疫反应中药复方药效物质基础研究，国家科技重大专项子课题，项目负责人

2. 基于sEH 和Keap1双靶点的分子配伍效应探讨中药旋覆花抗急性肺损伤的药效物质与作用机制研究，国家自然科学基金面上项目，项目负责人

3. 基于核受体FXR调控的中药泽泻逆转胆汁淤积的药效物质与作用规律研究，国家自然科学基金青年项目，项目负责人

4. 天津市第一批青年科技人才项目,天津市科协，项目负责人

5. 辽宁省兴辽英才计划青年拔尖人才项目，辽宁省科技厅，项目负责人

6. 中药钩藤抗抑郁药效物质基础与作用机制研究，辽宁省自然科学基金面上项目，项目负责人

7. 基于5-HT1A 受体中药钩藤抗抑郁药效物质与作用机制研究，大连市科技之星，项目负责人

8. 中华中医药学会（2022-2024 年度）青年人才托举工程项目，中华中医药学会，项目负责人

代表性成果：

1. Sun, C. P. (第一作者), Zhou, J. J., Yu, Z. L., Huo, X. K., Zhang, J., Morisseau, C., Hammock, B. D., Ma, X. C., 2022. Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal model. Proc. Natl. Acad. Sci. U. S. A. 119, e2118818119. (IF = 9.4)

2. Zhang, J., Zhang, M., Huo, X. K., Ning, J., Yu, Z. L., Morisseau, C.,  Sun, C. P. (共同通讯作者), Hammock, B. D., Ma, X. C., 2023. Macrophage inactivation by small molecule wedelolactone via targeting sEH for the treatment of LPS-induced acute lung injury. ACS Cent Sci 9, 440-456. (IF = 13.1)

3. Zhang, J., Zhang, M., Zhu, Q. M., Xu, X. R., Feng, Y. L., Lin, S., Qiu, F., Sun, C. P. (最后通讯作者), 2024. Allosteric regulation of Keap1 by 8beta-hydroxy-alpha-cyclocostunolide for the treatment of acute lung injury. Acta Pharm Sin B 14, 4174-4178. (IF = 14.8)

4. Zhang, J., Zhang, W. H., Morisseau, C., Zhang, M., Dong, H. J., Zhu, Q. M., Huo, X. K., Sun, C. P. (共同通讯作者), Hammock, B. D., Ma, X. C., 2023. Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate matter 2.5 exposure mediated lung injury. J. Hazard. Mater. 458, 131890. (IF = 12.2)

5. Zhu, Q. M., Wang, C., Liu, J. W., Zhang, R., Xin, X. L., Zhang, J., Sun, C. P. (共同通讯作者), Ma, X. C., 2024. Degradation profile of environmental pollutant 17beta-estradiol by human intestinal fungus Aspergillus niger RG13B1 and characterization of genes involved in its degradation. J. Hazard. Mater. 461, 132617. (IF = 12.2)

6. Gao, X., Sun, C. P. (共同第一作者), Yu, Z. L., Cang, J., Tian, X. G., Huo, X. K., Feng, L., Liu, X. G., Wang, C., Zhang, B. J., Ma, X. C., 2018. Correlation analysis between the chemical contents and bioactivity for the quality control of Alismatis Rhizoma. Acta Pharm Sin B 8, 242-251. (IF = 14.8)

7. Peng, Y. L., Chang, Y. B., Sun, C. P. (共同通讯作者), Wang, W. Y., Wang, C., Tian, Y., Zhang, B. J., Deng, S., Zhao, W. Y., Ma, X. C., 2022. Octacyclic and decacyclic ent-abietane dimers with cytotoxic activity from Euphorbia fischeriana steud. Chin. Chem. Lett. 33, 4261-4263. (IF = 9.4)

8. Zhang, J., Zhang, R., Li, W., Ma, X. C., Qiu, F., Sun, C. P. (最后通讯作者), 2023. IkappaB kinase beta (IKKbeta): Structure, transduction mechanism, biological function, and discovery of its inhibitors. Int. J. Biol. Sci. 19, 4181-4203. (IF = 8.2)

9. Zhang, J., Luan, Z. L., Huo, X. K., Zhang, M., Morisseau, C., Sun, C. P. (共同通讯作者), Hammock, B. D., Ma, X. C., 2023. Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury. Int. J. Biol. Sci. 19, 294-310. (IF = 8.2)

10. Jia, Y. X., Wang, N., Hui, S. W., Chang, J., Zhu, Q. M., Zhang, H. L., Zhang, J., Yan, J. K., Sun, C. P. (最后通讯作者), 2025. Discovery of soluble epoxide hydrolase inhibitors from Inula britannica: Inhibition kinetics, molecular dynamics simulation, biochemical, and in vitro cell-based studies. Int. J. Biol. Macromol. 306, 141704. (IF = 7.7)

11. Zhang, J., Yang, F. Y., Zhu, Q. M., Zhang, W. H., Zhang, M., Yi, J., Wang, Y., Zhang, H. L., Liang, G. B., Yan, J. K., Sun, C. P. (最后通讯作者), 2023. Inhibition effect of 1-acetoxy-6alpha-(2-methylbutyryl)eriolanolide toward soluble epoxide hydrolase: Multispectral analysis, molecular dynamics simulation, biochemical, and in vitro cell-based studies. Int. J. Biol. Macromol. 235, 123911. (IF = 7.7)

12. Zhao, W. Y., Zhang, X. Y., Zhou, M. R., Tian, X. G., Lv, X., Zhang, H. L., Deng, S., Zhang, B. J., Sun, C. P. (共同通讯作者), Ma, X. C., 2021. Natural soluble epoxide hydrolase inhibitors from Alisma orientale and their potential mechanism with soluble epoxide hydrolase. Int. J. Biol. Macromol. 183, 811-817. (IF = 7.7)

13. Yun, W. J., Zhang, X. Y., Liu, T. T., Liang, J. H., Sun, C. P. (共同通讯作者), Yan, J. K., Huo, X. K., Tian, X. G., Zhang, B. J., Huang, H. L., Ma, X. C., 2020. The inhibition effect of uncarialin A on voltage-dependent L-type calcium channel subunit alpha-1C: Inhibition potential and molecular stimulation. Int. J. Biol. Macromol. 159, 1022-1030. (IF = 7.7)

14. Lv, X., Bai, R., Yan, J. K., Huang, H. L., Huo, X. K., Tian, X. G., Zhao, X. Y., Zhang, B. J., Zhao, W. Y., Sun, C. P. (最后通讯作者), 2021. Investigation of the inhibitory effect of protostanes on human carboxylesterase 2 and their interaction: Inhibition kinetics and molecular stimulations. Int. J. Biol. Macromol. 167, 1262-1272. (IF = 7.7)

15. He, X., Zhao, W. Y., Shao, B., Zhang, B. J., Liu, T. T., Sun, C. P. (共同通讯作者), Huang, H. L., Wu, J. R., Liang, J. H., Ma, X. C., 2020. Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase. Int. J. Biol. Macromol. 158, 1362–1368. (IF = 7.7)

16. Sun, C. P. (第一作者), Yan, J. K., Yi, J., Zhang, X. Y., Yu, Z. L., Huo, X. K., Liang, J. H., Ning, J., Feng, L., Wang, C., Zhang, B. J., Tian, X. G., Zhang, L., Ma, X.C, 2020. The study of inhibitory effect of natural flavonoids toward beta-glucuronidase and interaction of flavonoids with beta-glucuronidase. Int. J. Biol. Macromol. 143, 349-358. (IF = 7.7)

17. Wang, Y. F., Xu, H., Feng, L., Shen, X. F., Wang, C., Huo, X. K., Tian, X. G., Ning, J., Zhang, B. J., Sun, C. P. (共同通讯作者), Deng, S., 2019. Oxidative coupling of coumarins catalyzed by laccase. Int. J. Biol. Macromol. 135, 1028-1033. (IF = 7.7)

18. Yi, J., Bai, R., An, Y., Liu, T. T., Liang, J. H., Tian, X. G., Huo, X. K., Feng, L., Ning, J., Sun, C. P. (共同通讯作者), Ma, X. C., Zhang, H. L., 2019. A natural inhibitor from Alisma orientale against human carboxylesterase 2: Kinetics, circular dichroism spectroscopic analysis, and docking simulation. Int. J. Biol. Macromol. 133, 184-189. (IF = 7.7)

19. Sun, C. P. (第一作者), Zhang, X. Y., Morisseau, C., Hwang, S. H., Zhang, Z. J., Hammock, B. D., Ma, X. C., 2021. Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. J. Med. Chem. 64, 184-215. (IF = 6.9)

20. Feng, Y. L., Xu, X. R., Zhu, Q. M., Chang, J., Zhang, H. L., Wang, N., Sun, J. B., Liu, J., Zhang, J., Sun, C. P. (最后通讯作者), 2024. Aucklandiae radix targeted PKM2 to alleviate ulcerative colitis: Insights from the photocrosslinking target fishing technique. Phytomedicine 134, 155973. (IF = 6.7)